There are a number of intriguing matchups on the Week 12 NFL odds board, including a must-see Sunday Night Football showdown between the top two teams in the NFC. The latest Week 12 NFL spreads list the San Francisco 49ers (9-1) as three-point home favorites over Aaron Rodgers and the Green Bay Packers (8-2). However, the Packers have dominated this series of late, winning 15 of their last 20 meetings against San Francisco.
Is Packers vs. 49ers one of the most exportable Week 12 NFL odds? Or is there better value on one of the divisional matchups happening across the league like Falcons vs. Buccaneers (+4.5) or Steelers vs. Bengals (+6.5)? Whether you’re looking to make a pick on one of those games, or searching other Week 12 NFL lines for value, be sure to see the latest NFL predictions from SportsLine’s proven computer model before locking in any NFL picks of your own.
How to make NFL picks
The model, which simulates every NFL game 10,000 times, is up over $7,000 for $100 players on its top-rated NFL picks since its inception four years ago. It’s on a 92-63 roll on top-rated picks that dates back to 2017, and last season, the model also ranked in the Top 10 on NFLPickWatch for the third year in a row on straight-up NFL picks and beat more than 96 percent of CBS Sports office pool players.
Anyone who has followed it has consistently beaten NFL odds and is way up. Now, the computer examined the latest Week 12 NFL odds and lines, simulated every snap, and its NFL predictions are in. First, here are this week’s NFL odds:
Week 12 NFL odds, spreads
- Indianapolis Colts at Houston Texans (-3.5, 45.5)
- Miami Dolphins at Cleveland Browns (-10.5, 44.5)
- Denver Broncos at Buffalo Bills (-4, 37)
- Pittsburgh Steelers at Cincinnati Bengals (+6.5, 39)
- New York Giants at Chicago Bears (-6, 40.5)
- Oakland Raiders at New York Jets (+2.5, 46.5)
- Carolina Panthers at New Orleans Saints (-9.5, 47)
- Tampa Bay Buccaneers at Atlanta Falcons (-4.5, 51.5)
- Detroit Lions at Washington Redskins (+3.5, 41.5)
- Seattle Seahawks at Philadelphia Eagles (-1.5, 48.5)
- Jacksonville Jaguars at Tennessee Titans (-3, 41.5)
- Dallas Cowboys at New England Patriots (-6.5, 45.5)
- Green Bay Packers at San Francisco 49ers (-3, 47.5)
- Baltimore Ravens at Los Angeles Rams (+3, 46.5)
NFL picks to back
We can tell you one of the model’s strongest NFL picks of the week comes in the matchup between the Oakland Raiders and New York Jets (+2.5) at MetLife Stadium.
NFL bettors who have backed the Raiders in recent weeks have seen plenty of returns. In fact, Oakland is 5-2 against the spread in its last seven games, and SportsLine’s model knows the Raiders have had New York’s number in their most recent meetings. The Raiders have covered the spread in four of their last five meetings against the Jets and will enter Sunday’s matchup full of confidence after winning three consecutive games.
Meanwhile, the Jets are just 2-8 in their last 10 games at home and have covered the spread just twice in their last 11 games against AFC West opponents. Plus, New York’s offense is averaging just 248.2 yards this season, the worst mark in the NFL. SportsLine’s model says Oakland covers against Sam Darnold and the Jets in almost 60 percent of simulations, while the computer has also found value on the under (46.5) because that hits in nearly 60 percent of simulations.
The model also has made the call against the spread, on the over-under, and on the money line for every other game on the Week 12 NFL schedule. It’s also projecting a Super Bowl contender to go down hard, so you need to see its NFL picks before locking in any of your own. Get every pick for every game here.
Who should you back against the spread, on the money line and the total in every Week 12 NFL game? And which Super Bowl contender goes down? Check out the latest NFL odds above, then visit SportsLine to see their Week 12 NFL cheat sheet, all from the model that is up over $7,000 on its top-rated NFL picks.