Wed, Dec 11, 2019

The Latest on Week 11 in the NFL (all times EST):

3:30 p.m.

The Philadelphia Eagles are missing three starters, including running back Jordan Howard, for their game against the New England Patriots.

Also ruled out are wide receiver Alshon Jeffery and linebacker Nigel Bradham. Howard has a shoulder injury, Jeffery and Bradham have ankle injuries

The AFC-leading Patriots are without starting safety Patrick Chung due to a chest injury.

In San Francisco, the 49ers will be without star tight end George Kittle for a second straight week because of injuries to his ankle and knee. San Francisco will have receiver Emmanuel Sanders active against the Arizona Cardinals after he left last week’s game with injured ribs.

The 49ers also are without starting left tackle Joe Staley (finger) and running back Matt Breida (ankle).

The Cardinals are expected to have their original offensive line back with right tackle Justin Murray returning from a knee injury. Murray’s return will allow Justin Pugh to go back to his original spot at left guard.

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